Coldwater disease prevention and control through vaccine development and diagnostic improvements

Our project focuses on examining strategies for managing coldwater disease (CWD), a prevalent challenge at many aquaculture facilities, in a more effective manner. We also aim to pinpoint bacterial genes that could potentially be instrumental in vaccine development and testing. Presently, the lack of a commercial vaccine for Flavobacterium psychrophilum strains, understood as the causative agent for CWD, increases these infrastructural challenges. The ultimate objective of this initiative is to bolster the capacities of aquaculturists to combat CWD by providing clear and useful information. 


  1. Identify potential vaccine candidates using in vivo-induced antigen technology (IVIAT) followed by screening with convalescent serum from trout
  2. Validate quantitative diagnostic assays (ELISA and ovarian fluid filtration FAT)
  3. Based on the results from objective 2; develop other assays (e.g. real-time quantitative PCR) for quantification of infection in ovarian fluid
  4. Develop an integrated outreach program to meet stakeholder needs

Project Summary

Duration: 4 years
Funded Date: 09/01/2007
Funding level: $251,404
Location: Idaho - ID, non-WRAC states, Washington - WA

University of Washington
School of Aquatic & Fishery Sciences

Box 355020, Seattle, WA 98195
1122 NE Boat St, Seattle, WA 98105


Grants and Funding